In the spring of 1992, Fr. Michael Engh, SJ, Professor of History, visited the Center for Ignatian Spirituality at Marquette University to learn of its ministry of the Spiritual Exercise of St. Ignatius of Loyola with faculty and staff. He then proposed to the LMU Jesuit Community the possibility of a similar center at the university.

In the fall of 1992, Fr. Tom Rausch, SJ, Rector of the LMU Jesuit Community, initiated a discernment process with the Jesuit Community and the university about the possible need of a center at LMU. Fr. Rausch, SJ, and Fr. Engh, SJ, convened lunchtime sessions with faculty and staff to discuss possible ways to respond to the growing desire for Ignatian formation.

Fr. Engh, SJ, served as the next Rector of the LMU Jesuit Community and continued this discernment process. He appointed Fr. Clancey Wallen, SJ, retired Professor of Mathematics, to begin guiding faculty and staff through the Spiritual Exercises of St. Ignatius of Loyola.  

In May of 1999, Fr. Michael Engh, SJ, and Fr. Thomas P. O'Malley, SJ, LMU President, signed an agreement establishing the Center for Ignatian Spirituality at LMU. The LMU Jesuit Community endowed the Center with a matched gift from the University Hill Foundation. In August, Fr. Engh appointed Fr. Tom Powers, SJ, as the first director. 

In January 2000, Fr. Powers began the ministry of the Center by using a parlor located in Ignatian Commons, the LMU Jesuit Residence. In August, the Center for Ignatian Spirituality moved to the Leavey Faculty Center and it was officially opened in September.

In January of 2003, Fr. Randy Roche, SJ, was appointed as the second director. In the fall, an advisory board composed of faculty and staff was created to advise the Center on its programs and finances. Sr. Frances Gussenhoven, RSHM, and Sr. Anne Hennessy, CSJ, consecutively collaborated in the spiritual and pastoral ministry of the Center.

Building facadeIn the summer of 2018, the Center for Ignatian Spirituality was relocated to Xavier Hall. Fr. Wayne Negrete, SJ, currently collaborates with Fr. Randy Roche, SJ, in the ministry of the Center.